Production of Itaconic Acid and Kojic Acid by a Species of Aspergillus

Relationship between morphology and itaconic acid production by Aspergillus terreus.

The morphology of filamentous fungi closely correlates with the productivity in submerged culture. Using itaconic acid (IA) production by Aspergillus terreus as a research model, the quantitative relationship between the growth form of A. terreus and IA production was investigated. IA fermentation was scaled up from shake flasks to a 7 L stirred tank bioreactor based on the quantitative relatio...

Production of aflatoxins and kojic acid by species of Aspergillus and Penicillium.

Itaconic Acid Production by Microorganisms: A Review

Itaconic acid (C5H6O4) is an organic acid with unique structure and characteristics. In order to promote the bio-based economy, the US-Department of Energy (DOE) assigned a “top-12” of platform chemicals, which include numerous of organic acids. In particular di-carboxylic acids, like itaconic acid, can be used as monomers for bio-polymers. Thus the need to produce itaconic acid attracts much a...

Production of Itaconic Acid through Submerged Fermentation Employing Different Species of Aspergillus

Itaconic acid was best produced by fungal species than bacterial species. The A. niger and A. terreus were known to be the best species for itaconic acid production among the different fungal species studied. However, there was no comprehensive study on using latest technologies for increasing the productivity at industrial level and it was not properly established. By keeping this in view, the...

Production of lovastatin and itaconic acid by Aspergillus terreus: a comparative perspective

Aspergillus terreus is a textbook example of an industrially relevant filamentous fungus. It is used for the biotechnological production of two valuable metabolites, namely itaconic acid and lovastatin. Itaconic acid serves as a precursor in polymer industry, whereas lovastatin found its place in the pharmaceutical market as a cholesterol-lowering statin drug and a precursor for semisynthetic s...